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当前位置: 首页 > 产品中心 > Tag_antibody > Hycult Biotech/CD96, Mouse, mAb 6A6 | Hycult Biotech/HM1105-100UG
商品详细Hycult Biotech/CD96, Mouse, mAb 6A6 | Hycult Biotech/HM1105-100UG
Hycult Biotech/CD96, Mouse, mAb 6A6  | Hycult Biotech/HM1105-100UG
Hycult Biotech/CD96, Mouse, mAb 6A6 | Hycult Biotech/HM1105-100UG
商品编号: HM1105-100UG
品牌: hycultbiotech
市场价: ¥7820.00
美元价: 4692.00
产地: 美国(厂家直采)
公司:
产品分类: 标签抗体
公司分类: Tag_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
The monoclonal antibody 6A6 recognizes mouse CD96. CD96 or T cell-Activated Increased Late Expression (TACTILE) is an ~67 kD immunoglobulin-like protein expressed on natural killer (NK) and T cells. CD96 belongs to the Ig-super family, consisting of three Ig-like domains and an extended serine/threonine/praline-rich stalk in the ectodomain. CD96 is upregulated upon T cell activation and is involved in engagement of diseased cells and cell movement towards areas of inflammation. Mouse CD96 binds to CD155 and nectin-1. CD96/CD155-interaction is preserved between man and mouse although both receptors are only moderately conserved in amino acid sequence. The monoclonal antibody 6A6 completely inhibits binding of CD96 to both recombinant mouse CD155 and mouse nectin-1. Also, T cell adhesion to insect cells expressing mCD155 is blocked by this monoclonal antibody, however, depending on the T cell subtype.The monoclonal antibody 6A6 was raised after immunization of rats with purified recombinant mCD96-hIgG1.
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。