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Hycult Biotech/Ficolin-2, Human, mAb GN4 | Hycult Biotech/HM2090-100UG
Hycult Biotech/Ficolin-2, Human, mAb GN4 | Hycult Biotech/HM2090-100UG
商品编号：
HM2090-100UG
品牌：
hycultbiotech
市场价：
¥8660.00
美元价：
5196.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
The monoclonal antibody GN4 recognizes human Ficolin-2, also known as L-ficolin. Ficolins are a family of pattern recognition molecules containing both a collagen-like domain and a fibrinogen-like domain that are capable of activating the complement system, through association with MASPs, on the surface of microorganisms. In human, three Ficolins are known: Ficolin-1 (M-ficolin), Ficolin-2 (L-ficolin), and Ficolin-3 (H-ficolin). Ficolin-1, is mainly expressed bymonocytes, granulocytes andlung cells and is present locally in areas of inflammation.Ficolin-2 (also L-ficolin, ficolin L, EBP-37 or hucolin) is produced primarily by the liver. The association between Ficolin-2 and MASPs/sMAP is Ca2+-dependent. MASPs in Ficolin-2-MASP complexes have proteolytic activities for C4, C2 and C3. Ficolin-2 also shows opsonic activity.
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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