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当前位置: 首页 > 产品中心 > monoclonal_antibody > Hycult生物技术公司/CD46,人类,单克隆抗体M177,FITC|Hycult生物技术公司/HM2103F-100UG
商品详细Hycult生物技术公司/CD46,人类,单克隆抗体M177,FITC|Hycult生物技术公司/HM2103F-100UG
Hycult生物技术公司/CD46,人类,单克隆抗体M177,FITC|Hycult生物技术公司/HM2103F-100UG
Hycult生物技术公司/CD46,人类,单克隆抗体M177,FITC|Hycult生物技术公司/HM2103F-100UG
商品编号: HM2103F-100UG
品牌: hycultbiotech
市场价: ¥8220.00
美元价: 4932.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
The monoclonal antibody M177 recognizes CD46, also designated membrane cofactor protein (MCP). CD46 is a 45-70 kDa protein with genetic and tissue-specific heterogeneity.- It is expressed on every cell and tissue, with the exception of erythrocytes. CD46 serves to inhibit complement activation on host tissue. It performs this function by serving as a cofactor which binds to C3b and C4b. This binding is permitted by factor I, a serine protease of plasma, to degrade C3b and C4b and serves to protect the host cell against autologous attack. It also serves as a receptor for measles virus. Four isoforms of CD46 predominate and arise by alternative splicing of a single CD46 gene. CD46 cDNA encodes a signal sequence followed by four complement control protein domains (also called short consensus repeats (SCR)). The monoclonal antibody M177 reacts with the SCR2 domain.
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。