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当前位置: 首页 > 产品中心 > monoclonal_antibody > Hycult Biotech/ICAM-1, Human, mAb HM.2, biotinylated | Hycult Biotech/HM2104BT-50UG
商品详细Hycult Biotech/ICAM-1, Human, mAb HM.2, biotinylated | Hycult Biotech/HM2104BT-50UG
Hycult Biotech/ICAM-1, Human, mAb HM.2, biotinylated  | Hycult Biotech/HM2104BT-50UG
Hycult Biotech/ICAM-1, Human, mAb HM.2, biotinylated | Hycult Biotech/HM2104BT-50UG
商品编号: HM2104BT-50UG
品牌: hycultbiotech
市场价: ¥3500.00
美元价: 2100.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
The monclonal antibody HM.2 reacts with the 90 kD glycoprotein Intracellular Adhesion Molecule-1 (ICAM-1). The adhesion molecule ICAM-1 belongs to the immunoglobulin superfamily, C2 subset; it is a ligand for the Integrins LFA-1 and MAC-1 and for CD43.ICAM-1 is a essential component in many immune-related processes. ICAM-1 links with receptors of the integrin family, thereby mediating cell-cell interactions and allowing for signal transduction. ICAM-1 interacts specifically with its receptors to induce a reversible adhesion interaction. For processes like T cell activation and leucocyte recruitment, normal immune function relies on ICAM-1. Therefore, it is understandable that alterations in ICAM-1 structure or expression are associated with immune disorders. It is important to properly understand the various functions and regulatory mechanisms of ICAM-1, the resulting disease-related failures, and the various treatments.ICAM-1 is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells. Upon cytokine stimulation, the concentrations greatly increase. ICAM-1 can be induced by interleukin-1 (IL-1) and tumor necrosis factor alpha (TNFalpha) and is expressed by the vascular endothelium, macrophages and lymphocytes
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。