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Hycult Biotech/Punctin-1, Human, mAb 1B2-8-2 | Hycult Biotech/HM2169-100UG
Hycult Biotech/Punctin-1, Human, mAb 1B2-8-2 | Hycult Biotech/HM2169-100UG
商品编号:
HM2169-100UG
品牌:
hycultbiotech
市场价:
¥6340.00
美元价:
3804.00
产品分类:
标签抗体
公司分类:
Tag_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Monoclonal antibody 1B2-8-2 reacts with Punctin-1 (ADAMTSL-1). Punctin-1 is a secreted moleculeresembling members of the family of proteases designated ADAMTS (a disintegrin-like andmetalloprotease domain with thrombospondin type I motif). ADAMTS proteases are secreted enzymes thatconsist of a metalloprotease domain (which provides the catalytic activity) and ancillary domains (whichprovide substrate, cell or extracellular matrix activity). Punctin-1 lacks the pro-metalloprotease and thedisintegrin-like domain typical of this family but contains other ADAMTS domains in precise order including4 thrombospondin-I repeats. Punctin-1 is an extracellular matrix protein in tissues and deposited into thecell substratum and localized towards the periphery of transfected cells. Punctin-1 and Punctin-2(ADAMTSL-3) are the first members of a novel family of ADAMTS-like proteins that appear to haveimportant functions in the extracellular matrix.Monoclonal antibody 1B2-8-2 recognizes the first thrombospondin repeat near the N-terminal and reactswith molecular species of 55 kDa or a doublet of 55 k Da and 60 kDa (glycosylated form). Note thatproteolysis of Punctin-1 has been described and additional smaller bands may also be obtained.
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。
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