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当前位置: 首页 > 产品中心 > monoclonal_antibody > 海科生物技术/乳铁蛋白,人,单克隆抗体265-1K1 |海科生物技术/HM2173-20UG
商品详细海科生物技术/乳铁蛋白,人,单克隆抗体265-1K1 |海科生物技术/HM2173-20UG
海科生物技术/乳铁蛋白,人,单克隆抗体265-1K1 |海科生物技术/HM2173-20UG
海科生物技术/乳铁蛋白,人,单克隆抗体265-1K1 |海科生物技术/HM2173-20UG
商品编号: HM2173-20UG
品牌: hycultbiotech
市场价: ¥1980.00
美元价: 1188.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
The monoclonal antibody 265-1K1 reacts with human lactoferrin (LF), an 80 kDa glycoprotein. Lactoferrin was first isolated from human milk and plays an important part in the immune system and helps to fight infections. Lactoferrin promotes the health of the gastro-intestinal system by improving the intestinal microbial balance. In addition, LF can be found in epithelia and most body fluids and secretions.Lactoferrin is secreted in plasma by neutrophils. Its plasma concentration also represents a positive relation to the total pool of neutrophils and the rate of neutrophil turnover. In inflammation lactoferrin is released from secondary granules of neutrophilic leukocytes into the extracellular medium. Therefore the extracellular lactoferrin concentration can be used as an index for neutrophil activation.Lactoferrin strongly binds to iron and this iron binding property is considered to be an important antimicrobial. Human lactoferrin binds to bacterial products through its highly positively charged N-terminus, it kills various bacteria, most probably by inducing intracellular changes in these bacteria without affecting the membrane permeability. Cleavage by pepsin of lactoferrin leads to the release of lactoferricin H. This 47 amino acid peptide has more antimicrobial activity than its precursor and it can inhibit the classical but not the alternative complement pathway.Lactoferrin also plays a role in signal transduction, immunomodulation and has antiadhesive, anticancer, antiviral activity.
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。