Hycult Biotech/DNAM-1，小鼠，单克隆抗体TX92/HM1137/100µg
商品编号：
HM1137
品牌：
hycultbiotech
市场价：
¥6432.00
美元价：
3859.20
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:DNAM-1,Mouse,mAbTX92
DNAXaccessorymolecule-1(DNAM-1)isa65kDatypeItransmembraneglycoproteinandamemberoftheimmunoglobulinsuperfamily.DNAM-1isconstitutivelyexpressedonamajorityofTcells,NKcellsandmacrophages.InteractionofDNAM-1withDNAM-1ligandsCD155andCD112inducesintercellularadhesion,infiltrationandcellsignaling,resultinginavarietyofcellularresponsesincludinginnateandadaptiveimmunities.
Specifications:
| Catalognumber | HM1137 |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100µg/ml)0.2µmfilteredantibodysolutioninPBS,containing0.1%bovineserumalbumin. |
| Application | Flowcytometry,Functionalstudies |
| ApplicationNotes | FC:AntibodyTX92stainstheextracellulardomainofDNAM-1.FS:AntibodyTX92hasaninhibitoryfunctionofDNAM-1bindingtotheligands.ItadditionallycausespartialdepletionofPBCD8+Tcells(Ref.1). |
| Use | Forflowcytometry,dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:25.Forfunctionalstudies,invitrodilutionshavetobeoptimizedinuser’sexperimentalsetting. |
| Immunogen | BW5417transfectantexpressingmouseDNAM-1,boostedwithDNAM-1-fcfusionprotein. |
| Isotype | RatIgG2b |
| Species | Mouse |
| Alias | DNAXaccessorymolecule-1,ClusterofDifferentiation226,PTA1 |
| References | 1.Yamashita,Yetal;Establishmentandcharacterizationofanovelanti-DNAM-1monoclonalantibody.MonoclonAntibimmunodiagnImmunother2013,32:60 |
| StorageandstABIlity | Productshouldbestoredat4°C.Underrecommendedstorageconditions,productisstableforatleastoneyear.Theexactexpirydateisindicatedonthelabel. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandfederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultfromtheuseorderivationofthisproduct. |
| Disease | Autoimmunity,Tumorimmunology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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