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当前位置: 首页 > 产品中心 > monoclonal_antibody > Hycult Biotech/SPLUNC1, Human, mAb 5F5B12 | Hycult Biotech/HM2314
商品详细Hycult Biotech/SPLUNC1, Human, mAb 5F5B12 | Hycult Biotech/HM2314
Hycult Biotech/SPLUNC1, Human, mAb 5F5B12  | Hycult Biotech/HM2314
Hycult Biotech/SPLUNC1, Human, mAb 5F5B12 | Hycult Biotech/HM2314
商品编号: HM2314
品牌: hycultbiotech
市场价: ¥7820.00
美元价: 4692.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
The monoclonal antibody 5F5B12 recognizes SPLUNC1. The human genome encodes eight different PLUNC (palate, lung, and nasal epithelium associated) proteins that share a predicted structural similarity. The 25 kDa SPLUNC1/BPIFA1 protein was the first identified PLUNC protein and issecreted in human sputum and tracheobronchial secretions, as well as in saliva, nasal lavage fluid, and in specific granules of human neutrophils. The biological function of SPLUNC1/BPIFA is not known, but structural similarities to BPI family proteins suggest that SPLUNC1/BPIFA may be involved in defense responses in the airways. This proposed function is supported by the finding that SPLUNC1 levels are elevated in chronic airway inflammation and that mice overexpressing SPLUNC1/BPIFA exhibit enhanced protection against P. aeruginosa.Moreover, the protein was reported to bind LPS and shown to play and essential role in pulmonary host defense against Klebsiella pneumoniae respiratory infection. The monoclonal antibody, 5F5B12, is specific for SPLUNC1/BPIFA and can be used for ELISA, western blot and immunohistochemistry
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。