4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:病理学诊断相关的抗体,蛋白质
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > monoclonal_antibody > Hycult Biotech/MASP-1, Human, Clone 4H2A9 | Hycult Biotech/HM2297
商品详细Hycult Biotech/MASP-1, Human, Clone 4H2A9 | Hycult Biotech/HM2297
Hycult Biotech/MASP-1, Human, Clone 4H2A9  | Hycult Biotech/HM2297
Hycult Biotech/MASP-1, Human, Clone 4H2A9 | Hycult Biotech/HM2297
商品编号: HM2297
品牌: hycultbiotech
市场价: ¥7820.00
美元价: 4692.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
The monoclonal antibody 4H2A9 reacts with the CCP1 domain, which is shared by MASP-1, MASP-3 and MAp-44. In total 5MASP proteins have been identified (MASP-1, MASP-2, MASP-3, MAp19 and MAp44) which are encoded by 2 genes. The MASP-2 gene gives rise to MASP2 and MAp19 due to alternative splicing, whereas the MASP-1 gene encodes a primary transcript which can be spliced to three different mRNAs coding for MASP-1, MASP-3 and MAp44 having molecular weights of 88, 89 and 44kDa, respectively. On the protein level MASP-1 and MASP-2 are shown to be responsible for complement activation through proteolytic cleavage of C2 and C4, whereas MASP-3 has been suggested to inhibit the generation of the C3 convertase. So far the role of the truncated proteases MAp44 and Map19 remain unknown. The monoclonal antibody 4H2A9 is suitable for western blotting and immunoprecipitation experiments. Moreover, the antibody can be used in immunoassays detecting MASP-1, MASP-3 and/or MAp44.
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。