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Hycult Biotech/MAp44, Human, clone 2D5B6 | Hycult Biotech/HM2296
Hycult Biotech/MAp44, Human, clone 2D5B6 | Hycult Biotech/HM2296
商品编号:
HM2296
品牌:
hycultbiotech
市场价:
¥7820.00
美元价:
4692.00
产品分类:
单克隆抗体
公司分类:
monoclonal_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
The monoclonal antibody 2D5B6 reacts specifically with human MAp-44, a protein of approximately 44kDa, which is encoded by an alternatively spliced mRNA of the MASP-1 gene. Up to now 5MASP proteinshave been identified (MASP-1, MASP-2, MASP-3, MAp19 and MAp44) which are encoded by 2 genes. The MASP-2 gene gives rise to MASP2 and MAp19 due to alternative splicing, whereas the MASP-1 gene encodes a primary transcript which can be spliced to three different mRNAs coding for MASP-1, MASP-3 and MAp44. On the protein level MASP-1 and MASP-2 are shown to be responsible for complement activation through proteolytic cleavage of C2 and C4, whereas MASP-3 has been suggested to inhibit the generation of the C3 convertase.So far the role of MAp44 remains elusive. However, recent research have shown that patients suffering from colorectal cancer have increased levels of MAp44 upon surgery as compared to Map44 levels in normal sera. The monoclonal antibody 2D5B6 is suitable for immunohistochemistry, western blotting as well as use in immunoassays.
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。
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