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当前位置: 首页 > 产品中心 > monoclonal_antibody > Hycult Biotech/Lipid A, mAb 26-5 | Hycult Biotech/HM6009
商品详细Hycult Biotech/Lipid A, mAb 26-5 | Hycult Biotech/HM6009
Hycult Biotech/Lipid A, mAb 26-5  | Hycult Biotech/HM6009
Hycult Biotech/Lipid A, mAb 26-5 | Hycult Biotech/HM6009
商品编号: HM6009
品牌: hycultbiotech
市场价: ¥7820.00
美元价: 4692.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
The monoclonal antibody 26-5 recognizes lipid A. The lipid A domain of lipopolysaccharide (LPS) is aunique, glucosamine-based phospholipid that makes up the outer monolayer of the outer membrane ofmost gram-negative bacteria.Lipid A is responsible for the endotoxic activities of LPS, and a heteropolysaccharide. Theheteropolysaccharide generally consists of an oligosaccharide termed the core region. This core regionis in some bacterial families composed of repeating oligosaccharide units, the so-called O chain. Thelipid A moiety of LPS is detected by the TLR4/MD2 receptor of the mammalian innate immune system.Picomolar levels of lipid A induce macrophages to synthesize potent mediators of inflammation, such asTNF-α and IL-1β. Furthermore, lipid A activates the production of costimulatory molecules required foradaptive immunity and stimulates tissue factor production in mononuclear and endothelial cells. Allthese events are desirable for clearing local infections.
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。