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当前位置: 首页 > 产品中心 > monoclonal_antibody > Hycult Biotech/TLR4, Human, mAb 3C3, biotinylated | Hycult Biotech/HM2247BT
商品详细Hycult Biotech/TLR4, Human, mAb 3C3, biotinylated | Hycult Biotech/HM2247BT
Hycult Biotech/TLR4, Human, mAb 3C3, biotinylated  | Hycult Biotech/HM2247BT
Hycult Biotech/TLR4, Human, mAb 3C3, biotinylated | Hycult Biotech/HM2247BT
商品编号: HM2247BT
品牌: hycultbiotech
市场价: ¥4000.00
美元价: 2400.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
The monoclonal antibody 3C3 reacts with human Toll-like receptor 4 (TLR4, CD284). TLRs belong to a family of proteins that specifically recognize and sense microbial products. They are highly conserved throughout evolution. In Drosophila, toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defences. TLRs identified as type I transmembrane signalling receptors act as innate immune recognition receptors against many pathogens.TLR4 is a functional receptor for gram-negative bacterial lipopolysaccharides (LPS). TLR4 associates with MD-2 which is absolutely required for LPS-induced activation of TLR4. TLR4 has been identified next to MD-2 and CD14 as a receptor that is central to the innate immune response to LPS of Gram-negative bacteria.The monoclonal antibody 3C3 is a TLR4 function-blocking antibody that is useful for studies on the role of TLR4 as a receptor for LPS induced cytokine production by TLR4 bearing cells.
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。