Hycult Biotech/CD96, Human, mAb NK92.39/HM2210/100 µg
商品编号：
HM2210
品牌：
hycultbiotech
市场价：
¥9500.00
美元价：
5700.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:CD96,Human,mAbNK92.39
ThemonoclonalantibodyNK92.39reactswithCD96,alsoknownasTcell-activatedincreasedlateexpression(Tactile).CD96promotesnaturalkiller(NK)celladhesiontotargetcellsexpressingthepoliovirusreceptor(PVRorCD155).FurThermoreCD96stimulatescytotoxicityofactivatedNKcells,andmediatesacquisitionofPVRfromtargetcells.ThismeansNKcellshaveduetothereceptorCD96adualreceptorsystemthatrecognizesnectinsandnectin-likemoleculesontargetcellsandmediatesNKcellsadhesionandtriggeringofeffectorfunctions.AsPVRishighlyexpressedincertaintumors,thisreceptorsystemmaybecriticalforNKcellrecognitionoftumors.ThemonoclonalantibodyNK92.39blocksbindingofsolublepoliovirusreceptor(PVR)toNK92cells.
Specifications:
| Catalognumber | HM2210 |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100µg/ml)0.2µmfilteredantibodysolutioninPBS,containing0.1%bovineserumalbumin. |
| Application | Flowcytometry,Functionalstudies |
| Use | Forflowcytometrydilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50.ForfunctionalstudiesinvitrodilutionshavetobemadeaccordingtotheamountsofCD96tobeinactivated. |
| Isotype | MouseIgG1 |
| Species | Human |
| References | Fuchs,Aetal;Cuttingedge:CD96(Tactile)promotesNKcell-targetcelladhesionbyinteractingwiththepoliovirusreceptor(CD155).JImmunol2004,172:3994 |
| StorageandstABIlity | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
| Disease | Tumorimmunology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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