Hycult Biotech/MRP-14, Human, mAb 1H9/HM2176/100 µg
商品编号：
HM2176
品牌：
hycultbiotech
市场价：
¥7752.00
美元价：
4651.20
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:MRP-14,Human,mAb1H9
Themonoclonalantibody1H9recognizestheKPpLepitopeintheCterminalregionoftheS100A9(MRP-14)protein.Thecalcium-binding,migrationinhibitoryfactor-relatedproteins,MRP-8(S100A8)andMRP-14(S100A9)belongtotheS100proteinfamily.Theexpressionoftheseproteinsislargelyconfinedtothecytosolofneutrophilsandmonocytes.Thecomplexformationoftheseproteinsisacalcium-dependentprocess.TheS100A8/A9heterocomplex,alsocalledMRP-8/MRP-14complexorcalprotectin,comprises60%ofthecytoplasmicproteinfractionofcirculatingpolymorphonucleargranulocytesandisalsofoundinmonocytes,macrophagesandilealtissueeosinophils.Ininflammatoryconditionssmallvenuelesstainwithbothanti-S100A8andS100A9.Thestainingofthetwosubunitsisalwayscoincident.TheS100A8/A9complexhasantibacterial,antifungalandimmunomodulatingandantiproliferativeeffects.Besidesthisitisapotentchemotacticfactorforneutrophils.
Specifications:
| Catalognumber | HM2176 |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100µg/ml)0.2µmfilteredantibodysolutioninPBS,containing0.02%sodiumazideand0.1%bovineserumalbumin. |
| Application | Flowcytometry,Immunoassays,Westernblot |
| Use | ForflowcytometryandWesternblottingdilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:10. |
| Isotype | MouseIgG1 |
| Species | Human |
| Alias | S100A9 |
| References | Robinson,Metal;TheS100familyheterodimer,MRP-8/14,bindswithhighaffinitytoheparinandheparansulfateglycosaminoglycansonendothelialcells.JBiolChem2002,277:3658 |
| StorageandstABIlity | Productshouldbestoredat4°C.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
| Disease | Cardiologyandmetabolism,Gastroenterology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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