Hycult Biotech/Arginase 1, Human, mAb 9C5/HM2163/100 µg
商品编号：
HM2163
品牌：
hycultbiotech
市场价：
¥7752.00
美元价：
4651.20
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:Arginase1,Human,mAb9C5
Monoclonalantibody9C5reactsspecificallywithArginaseI,thefinalenzymeintheureacycle,whichisresponsIBLeforthehydrolysisofargininetoureaandornithine.Thehighestconcentrationoftheenzymeispresentintheliverinwhichthebulkofureagenesisoccurs.Twotypesofarginasesareknown:ArginaseIandII.ThecytosolicenzymefoundprimarilyinliverisArginaseI,a35kDproteinthatcirculatesastrimer.ArginaseIIisexclusivelylocatedinthemitochondrion.ArginaseIisnexttotheliverinmanalsoexpressedbymaturefetalandadultredbloodcellsandactivatedmonocyticcells.DuringinflammationinductionofArginaseIbyinflammatorycytokinesinmonocyticcellsisconsideredtoleadtoalocaldepletionofarginineresultinginamicroenvironmentthatpreventsnitricoxideproductionandargininedependentTcellfunction.ArginaseIIisexpressedbykidney,nucleatedredbloodcells,brain,spinalcord,gastro-intestinaltract,mammaryglandandprostate.EnhancedcirculatingArginaseIlevelshavebeenreportedaftersurgery,followinghaemorrhageandinasthmaticpatients.MeasurementofcirculatingArginaseIhasbeenusedexperimentallyasrapidMarkerforliverinjury.
Specifications:
| Catalognumber | HM2163 |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100μg/ml)0.2μmfilteredproteinGpurifiedantibodysolutioninPBS,containing0.02%sodiumazideand0.1%bovineserumalbumin. |
| Application | Frozensections,Immunoassays,Immunoprecipitation |
| ApplicationNotes | IA:theantibodycanbeusedasdetectionantibody. |
| Use | Dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
| Immunogen | Recombinanthumantype-1arginase |
| Isotype | MouseIgG1 |
| Species | Human |
| References | 1.Ikemoto,Metal;AusefulELISAsystemforhumanliver-typearginase,anditsutilityindiagnosisofliverdiseases.ClinBiochem2001,34:455 |
| StorageandstABIlity | Productshouldbestoredat4°.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsibleforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
| Disease | Autoimmunity,Tumorimmunology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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