Hycult Biotech/CD11b, Human, mAb Bear-1/HM2125/100 µg
商品编号：
HM2125
品牌：
hycultbiotech
市场价：
¥7752.00
美元价：
4651.20
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:CD11b,Human,mAbBear-1
CD11bisanalphachainintegrinthatisexpressedasheterodimernoncovalentlyassociatedwithCD18.CD11bisalsodesignatedasCR3,Mac-1,Mo-1inintegrinalphaMsubunitandhasamolecularweightof165-170kDa.TheproteinmediatesPMNandmonocytesadherencetoendotheliumandsubsequentlyPMNextravasationtositesofinflammation.CD11b/CD18interactswithbothmatrixandcellsurfaceproteinsincludingthecomplementcomponentiC3b,extracellularmatrixproteinsandthethirdextracellulardomainofCD54.CD11bisexpressedonhumanNK-cells,monocytes,granulocytes,T-cells,B-cellsanddendriticcells.Afteractivationtheexpressionisupregulated.Bear-1reactswiththeCD11balphachainoftheCD11b/CD18(p165,95)integrinheterodimercomplex.
Specifications:
| Catalognumber | HM2125 |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100µg/ml)0.2µmfilteredantibodysolutioninPBS,containing0.02%sodiumazideand0.1%bovineserumalbumin. |
| Application | Flowcytometry,Frozensections,Immunoprecipitation |
| Use | Forimmunohistologyandflowcytometrydilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:10. |
| Isotype | MouseIgG1 |
| Species | Human |
| Alias | CR3,Mac-1,Mo-1inintegrinalphaM |
| References | 1.Keizer,Getal;BiochemicalandfunctionalcharacteristicsofthehumanleukocytemembraneantigenfamilyLFA-1,Mo-1andp150,95.EurJImmunol1985,15:1142 2.Watanabe,Aetal;Effectsofanti-CD11a,anti-CD11bandantiCD18onhistaminereleasefromhumanbasophilsprimedwithIL-3.IntArchAllergyImmunl1992,98:308 |
| StorageandstABIlity | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
| Disease | Tumorimmunology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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