Hycult Biotech/Ficolin-2, Human, mAb GN5/HM2091/100 µg
商品编号：
HM2091
品牌：
hycultbiotech
市场价：
¥10320.00
美元价：
6192.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:Ficolin-2,Human,mAbGN5
ThemonoclonalantibodyGN5recognizeshumanFicolin-2,alsoknownasL-ficolin.Ficolinsareafamilyofpatternrecognitionmoleculescontainingbothacollagen-likedomainandafibrinogen-likedomainthatarecapableofactivatingthecomplementsystem,throughassociationwithMASPs,onthesurfaceofmicroorganisms.Inhuman,threeFicolinsareknown:Ficolin-1(M-ficolin),Ficolin-2(L-ficolin),andFicolin-3(H-ficolin).Ficolin-1,ismainlyexpressedbymonocytes,granulocytesandlungcellsandispresentlocallyinareasofinflammation.
Ficolin-2/P35(alsoL-ficolin,ficolinL,EBP-37orhucolin)isproducedprimarilybytheliver.TheassociationbetweenFicolin-2/P35andMASPs/sMAPisCa2+-dependent.MASPsinFicolin-2/P35-MASPcomplexeshaveproteolyticactivitiesforC4,C2andC3.Ficolin-2/P35alsoshowsopsonicactivity.
Ficolin-2/P35(alsoL-ficolin,ficolinL,EBP-37orhucolin)isproducedprimarilybytheliver.TheassociationbetweenFicolin-2/P35andMASPs/sMAPisCa2+-dependent.MASPsinFicolin-2/P35-MASPcomplexeshaveproteolyticactivitiesforC4,C2andC3.Ficolin-2/P35alsoshowsopsonicactivity.
Specifications:
| Catalognumber | HM2091 |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100μg/ml)0.2μmproteinGpurifiedantibodysolutioninPBS,containing0.1%bovineserumalbuminand0.02%sodiumazide. |
| Application | Frozensections,Immunoassays,Immunoprecipitation,Westernblot |
| ApplicationNotes | W:Anon-reducedsampletreatmentandSDS-Pagewasused.Thebandsizeis35kDa. IHC-F:TissuesectionswerefixedinacetoneandpretreatedwithperoxidaseblockoftheDakokit5min.inthedarkatRTtoquenchendogenousperoxidases. |
| Use | Dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
| Isotype | MouseIgG1 |
| Species | Human |
| Crossreactivity | Rat-Yes |
| Alias | Ficolin-2/P35,L-ficolin,ficolinL,EBP-37,hucolin,37kDaelastin-bindingprotein,Collagen/fibrinogendomain-containingprotein2,Ficolin-B,Ficolin-beta Genename:FCN2,FCNL |
| References | 1.Matsushita,Metal;Activationofthelectincomplementpathwaybyficolins.IntImmunopharmacol2001,1:359 2.Matsushita,Metal;ActivationofthelectincomplementpathwaybyH-ficolin(Hakataantigen).JofImmunol2002,168:35023.Matsushita,Metal;Theroleofficolinsininnateimmunity.Immunobiol2002,205:490 |
| StorageandstABIlity | Productshouldbestoredat4°C.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
| Disease | Cardiologyandmetabolism,Infectiousdiseases |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
联络我们
