Hycult Biotech/Ficolin-3, Human, mAb 4H5/HM2089/100 µg
商品编号：
HM2089
品牌：
hycultbiotech
市场价：
¥10320.00
美元价：
6192.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:Ficolin-3,Human,mAb4H5
Themonoclonalantibody4H5recognizeshumanFicolin-3,alsoknownasH-ficolin.Ficolinsareafamilyofpatternrecognitionmoleculescontainingbothacollagen-likedomainandafibrinogen-likedomainthatarecapableofactivatingthecomplementsystem,throughassociationwithMASPs,onthesurfaceofmicroorganisms.Inhuman,threeFicolinsareknown:Ficolin-1(M-ficolin),Ficolin-2(L-ficolin),andFicolin-3(H-ficolin).Ficolin-1,ismainlyexpressedbymonocytes,granulocytesandlungcellsandispresentlocallyinareasofinflammation.Ficolin-3(alsoHakataantigen,H-ficolinorficolinH)isproducedbytheliverandbythelung.Ficolin-3isassociatedwiththreetypesofMASPsandsMAP,thiscomplexactivatesC4,C2andC3inthefluidphase.
Specifications:
| Catalognumber | HM2089 |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100µg/ml)0.2µmfilteredantibodysolutioninPBS,containing0.02%sodiumazideand0.1%bovineserumalbumin. |
| Application | Frozensections,Immunoassays,Immunoprecipitation |
| Isotype | MouseIgG1 |
| Species | Human |
| References | 1.Matsushita,Metal;Activationofthelectincomplementpathwaybyficolins.IntImmunopharmacol2001,1:359 2.Matsushita,Metal;ActivationofthelectincomplementpathwaybyH-ficolin(Hakataantigen).JofImmunol2002,168:3502 3.Matsushita,Metal;Theroleofficolinsininnateimmunity.Immunobiol2002,205:490 4.Kuraya,Metal;ExpressionofH-ficolin/Hakataantigen,mannose-bindinglectin-associatedserineprotease(MASP)-1andMASP-3byhumangliomacelllineT98G.IntImmunol2003,15:109 |
| StorageandstABIlity | Productshouldbestoredat4°C.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
| Disease | Autoimmunity,Cardiologyandmetabolism |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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