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Hycult Biotech/L-FABP, Human, mAb L2B10, biotinylated/HM2050/50 µg

Hycult Biotech/L-FABP, Human, mAb L2B10, biotinylated/HM2050/50 µg
商品编号:
HM2050
品牌:
hycultbiotech
市场价:
¥6192.00
美元价:
3715.20
产品分类:
单克隆抗体
公司分类:
monoclonal_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description:L-FABP,Human,mAbL2B10,biotinylated
ThebiotinylatedmonoclonalantibodyL2B10recognizeshumanliverfattyacidbindingprotein(L-FABP)ofbothnaturalandrecombinantorigin.TheL-FABPproteinisderivedfromthehumanFABP1gene.FABPsaresmallintracellularproteins(~13-14kDa)withahighdegreeoftissuespecificitythatbindlongchainfattyacids.Theyareabundantlypresentinvariouscelltypesandplayanimportantroleintheintracellularutilizationoffattyacids,transportandmetabolism.ThereareatleastninedistincttypesofFABP,eachshowingaspecificpatternoftissueexpression.Duetoitssmallsize,FABPleaksrapidlyoutofischemicallydamagednecroticcellsleADIngtoariseinserumlevels.Ischemicallydamagedtissuesarecharacterizedhistologicallybyabsence(orlowpresence)ofFABPfacilitatingrecognitionofsuchareas.L-FABPislocalizedintheliver,kidneyandintestinalepithelium.ThemonoclonalantibodyL2B10isusefultodetectischemicareasofhumanliver.FurThermore,theantibodycanbeusedforthepurificationofhumanL-FABP.
Specifications:
Catalognumber | HM2050 |
---|---|
Producttype | Monoclonalantibodies |
Quantity | 50µg |
Formulation | 0.5ml(100µg/ml)0.2µmfilteredbiotinylatedantibodysolutioninPBS,containing0.1%bovineserumalbuminand0.02%sodiumazide. |
Conjugate | Biotin |
Application | Frozensections,Immunoassays,Westernblot |
Use | ForimmunohistologyandWesternblotting,dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
Isotype | RatIgG2b |
Species | Human |
Crossreactivity | Baboon-Yes,Human-Yes,Rat-Yes,Swine-Yes |
Alias | FABP1 |
References | Bax,Detal;High-gradedysplasiainBarrett"sesophagusisassociatedwithincreasedexpressionofcalgranulinAandB.ScandJGastroenterology2007,42:902 |
StorageandstABIlity | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandfederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseorderivationofthisproduct. |
Disease | Cardiologyandmetabolism,Nephrology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。
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