Hycult Biotech/L-FABP, Human, mAb L2B10/HM2049/100 µg
商品编号：
HM2049
品牌：
hycultbiotech
市场价：
¥7200.00
美元价：
4320.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:L-FABP,Human,mAbL2B10
ThemonoclonalantibodyL2B10recognizeshumanliverfattyacidbindingprotein(L-FABP)ofbothnaturalandrecombinantorigin.TheL-FABPproteinisderivedfromthehumanFABP1gene.FABPsaresmallintracellularproteins(~13-14kDa)withahighdegreeoftissuespecificitythatbindlongchainfattyacids.Theyareabundantlypresentinvariouscelltypesandplayanimportantroleintheintracellularutilizationoffattyacids,transportandmetabolism.ThereareatleastninedistincttypesofFABP,eachshowingaspecificpatternoftissueexpression.Duetoitssmallsize,FABPleaksrapidlyoutofischemicallydamagednecroticcellsleADIngtoariseinserumlevels.Ischemicallydamagedtissuesarecharacterizedhistologicallybyabsence(orlowpresence)ofFABPfacilitatingrecognitionofsuchareas.L-FABPislocalizedintheliver,kidneyandintestinalepithelium.ThemonoclonalantibodyL2B10isusefultodetectischemicareasofhumanliver.FurThermore,theantibodycanbeusedforthepurificationofhumanL-FABP.
Specifications:
| Catalognumber | HM2049 |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100μg/ml)0.2μmproteinGpurifiedantibodysolutioninPBS,containing0.1%bovineserumalbuminand0.02%sodiumazide. |
| Application | Frozensections,Immunoassays,Paraffinsections,Westernblot |
| ApplicationNotes | P:ForantigenretrievalbothTris-HCLandglycinebuffercanbeused. W:Reducedsampletreatment.Thebandsizeis~15kDa. |
| Use | Dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
| Isotype | MouseIgG2b |
| Species | Human |
| Crossreactivity | Baboon-Yes,Canine-Yes,Human-Yes,Rat-Yes,Swine-Yes |
| Alias | Humanliverfattyacidbindingprotein,FABP1,Liver-typefattyacid-bindingprotein Genename:FABP1,FABPL |
| References | 1.Bax,Detal;High-gradedysplasiainBarrett"sesophagusisassociatedwithincreasedexpressionofcalgranulinAandB.ScandJGastroenterology2007,42:902 |
| StorageandstABIlity | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandfederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseorderivationofthisproduct. |
| Disease | Cardiologyandmetabolism,Nephrology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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