Hycult Biotech/TNF-alpha, Human, mAb T1/HM2024/100 µg
商品编号：
HM2024
品牌：
hycultbiotech
市场价：
¥6960.00
美元价：
4176.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:TNF-alpha,Human,mAbT1
Theantibodyreactswithfreesoluble(17kDa)andmembrane(26kDa)humanTNF-alpha.TheantibodyinhibitstheBIOLOGicalactivityofbothforms.ItdoesnotreactwithreceptorboundTNF-alpha.ItcanbeausefultooltodiscriminatebetweenthemembraneformofTNFexpressedonproducercellsandtheproteolyticallycleaved,solubleTNF-alphaboundtoitscognatecellmembranereceptors(TNF-RIandTNF-RII).Forthispurposewerecommendtousethisantibodyincombinationwiththeanti-TNF-alphaantibodyHM2026,whichrecognizessoluble,membraneandreceptorboundTNF-alpha.
Specifications:
| Catalognumber | HM2024 |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100μg/ml)0.2μmproteinGpurifiedantibodysolutioninPBS,containing0.1%bovineserumalbumin. |
| Application | Flowcytometry,Functionalstudies,Immunoassays,Westernblot |
| ApplicationNotes | FS:ThemonoclonalantibodyT1canbeusedforinhibitionofthebiologicalactivityofTNF-alpha. W:AreducedsampletreatmentandSDS-Pagewasused.Thebandsizeis17kDa. |
| Use | Dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50.Forfunctionalstudies,invitrodilutionshavetobeoptimizedinuser’sexperimentalsetting. |
| Immunogen | BALB/cmicewithhuTNF,fusionofspleencellswithNSOmyelomacells(ref.1) |
| Isotype | MouseIgG1 |
| Species | Human |
| Alias | Tumornecrosisfactor,Cachectin,Tumornecrosisfactorligandsuperfamilymember2,Tumornecrosisfactor,membraneform,C-domain2,Tumornecrosisfactor,solubleform Genename:TNFA,TNFSF2 |
| References | 1.Gerspach,Jetal;Detectionofmembrane-boundTumorNecrosisFactor(TNF):ananalysisofTNF-specificreagents.MicroscResTech2000,50:243 |
| StorageandstABIlity | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseorderivationofthisproduct. |
| Disease | Autoimmunity,Gastroenterology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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