Hycult生物技术公司/α-防御素6,人,肽| Hycult生物技术公司/HC2137
商品编号:
HC2137
品牌:
hycultbiotech
市场价:
¥7380.00
美元价:
4428.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Defensins are small cysteine-rich cationic peptides containing three or four disulfide bridges. They are divided into families on the basis of the spatial distribution of their cysteine residues.Three families, the α-, β- and θ-defensins, can be distinguished in mammals. α- and β-defensins are characterized by antiparallel β-sheet structures stabilized by three disulfide bonds. The θ-defensins are found in rhesus monkey and some other non-human primates but not in human, chimpanzee and gorilla. They consist of two nine amino acid peptides derived from different precursor proteins joined by head-to-tail cyclization. Defensins protect human barriers from commensal and pathogenic microorganisms. Human α-defensin 6 (HD-6 with sequence AFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL) is produced exclusively by small intestinal paneth cells. It is an antimicrobial peptide acting via 2 distinct antimicrobial mechanisms: HD-6 kills specific microbes depending on the local reducing environmental conditions, whereas known microbial trapping by extracellular net structures is independent of the reducing milieu.
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。
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