Hycult Biotech/Spi-6, Mouse, pAb/HP8035/100 µg
商品编号：
HP8035
品牌：
hycultbiotech
市场价：
¥7752.00
美元价：
4651.20
产品分类：
多克隆抗体
公司分类：
Polyclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:Spi-6,Mouse,pAb
ThepolyclonalantibodyrecognizesmouseSpi-6,alsoknownasserpinB9,acytoplasmicserineproteaseinhibitorof~42kD.Spi-6isexpressedindendriticcells,lymphocytesandspecificcelltypesatimmune-privilegedsites.ItinactivatesgranzymeB,anaturaloccurringinducerofprogrammedcelldeath.Assuch,Spi-6functionsasanti-apoptoticprotein.IncytotxicTcells(CTL),Spi-6isrequiredtoprotectclonalbursts(expansion)fromgranzymeBinducedcelldeath.However,itisnotrequiredforthedevelopmentofmemorycells.ExpressionofSPI-6isofcrucialimportanceintheescapeofseveraltumorsfromaCTLresponseandis,therefore,aparameterthatinfluencesthefeasibilityofCTL-mediatedimmunotherapyofcancer.ThepolyclonalantibodyshowsnocrossreactivitywithmouseproteinsrelatedtoSpi-6.
Specifications:
| Catalognumber | HP8035 |
|---|---|
| Producttype | Polyclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100µg/ml)0.2µmfilteredantibodysolutioninPBS,containing0.1%bovineserumalbuminand0.02%sodiumazide. |
| Application | Flowcytometry,Immunoassays,Westernblot |
| Use | ForflowcytometryandWesternblotting,dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
| Immunogen | RecombinantGST-Spi-6 |
| Isotype | RabbitIg |
| Species | Mouse |
| Alias | Cytoplasmicantiproteinase3,serpinB9,PI-9 |
| References | 1.Zhang,Metal;DifferentialsurvivalofcytotoxicTcellsandmemorycellprecursors.JImmunol2007,178:3483 2.Zhang,Metal;Serineproteaseinhibitor6-deficientmicehaveincreasedneutrophilimmunitytoPseudomonasaeruginosa.JImmunol2007,179:4390 |
| StorageandstABIlity | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseorderivationofthisproduct. |
| Disease | Tumorimmunology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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