海考特生物技术/VG5Q,小鼠,pAb/HP8017/100µg
商品编号:
HP8017
品牌:
hycultbiotech
市场价:
¥9288.00
美元价:
5572.80
产品分类:
多克隆抗体
公司分类:
Polyclonal_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description:VG5Q,Mouse,pAb
ThepolyclonalantibodyreactswithmouseVG5Q,a84kDaprotein.VG5QfunctionsasanangiogenicfactorinpromotingangiogenesisandsuppressionofVG5Qexpressioninhibitsvesselformation.Angiogenicfactorsarecriticaltotheinitiationofangiogenesisandmaintenanceofthevascularnetwork.Angiogenesishasanessentialroleinpathologicalconditionssuchascancerandvariousischaemicandinflammatorydiseases.VG5Qcanbindtoendothelialcellsandpromotecellproliferation,suggestingthattheproteinmayactinanautocrinefashion.VG5QinteractswithTWEAK(alsoknownasTNFSF12),anothersecretedangiogenicfactor.VG5Qshowsstrongexpressioninbloodvesselsandissecretedwhenvesselformationisinitiated.VG5Qproteinwasdetectedmostlyinthecytoplasmandaroundthenucleiofhumanmicrovascularendothelialcells(HMVECs).FurThermoreVG5Qisdetectedinhumanumbilicalveinendothelialcells(HUVECs),humanheartfibroblast(HHF)andovariancancercells(OV-3),butlowexpressionwasdetectedinkidneycancercells(RP-45),HeLaCellsandbladdercancercells.
Specifications:
Catalognumber | HP8017 |
---|---|
Producttype | Polyclonalantibodies |
Quantity | 100µg |
Formulation | 1ml(100µg/ml)0.2µmfilteredantibodysolutioninPBS,containing0.02%sodiumazideand0.1%bovineserumalbumin. |
Application | Frozensections,Immunoassays,Immunoprecipitation,Paraffinsections,Westernblot |
Use | ForWesternblottingandimmunohistologydilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:10. |
Isotype | RabbitIg |
Species | Mouse |
References | 1.Tian,Xetal;IdentificationofanangiogenicfactorthatwhenmutatedcausessusceptibilitytoKlippel-Trenaunaysyndrome.Nature2004,427:640 |
StorageandstABIlity | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
Disease | Cardiologyandmetabolism,Tumorimmunology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。
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