Hycult Biotech/C3, Mouse, pAb/HP8012/100 µg
商品编号：
HP8012
品牌：
hycultbiotech
市场价：
¥7752.00
美元价：
4651.20
产品分类：
多克隆抗体
公司分类：
Polyclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:C3,Mouse,pAb
ThecomplementfactorC3consistsofanalpha-andabeta-chain.C3isacentralfactorinthecomplementcascade.ItiscentraltothealternativepathwaythatleadstotheC3convertaseC3bBb.TheclassicalandmannosebindinglectinactivationpathwaysleadtotheC3convertaseC4b2a.TheseconvertasescleaveC3resultinginC3aandC3b.Furtherdegradationleadstoformationofthealpha-chainproductsC3d,C3gandC3c.C3isanacutephaseproteinthatisproducedbyawiderangeoftissuesincludingrenalepithelialcellsandhepatocytes.
Specifications:
| Catalognumber | HP8012 |
|---|---|
| Producttype | Polyclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100μg/ml)0.2μmfilteredproteinGpurifiedantibodysolutioninPBS,containing0.1%bovineserumalbuminand0.02%sodiumazide. |
| Application | Frozensections,Immunofluorescence,Paraffinsections,Westernblot |
| ApplicationNotes | F:SectionswerepermeABIlizedincoldacetonefor10minutes. P:EpitoperetrievalfortheFFPEsectionswasperformedusingthePT-module(LabVision)withheatinducedepitoperetrievalpH9(HIER). |
| Use | Dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
| Isotype | RabbitIg |
| Species | Mouse |
| Alias | ComplementcomponentC3,HSE-MSF Genename:C3 |
| PositiveControl | Kidney,spleen |
| References | 1.Cashman,Setal;Expressionofcomplementcomponent3(C3)fromanadenovirusleadstopathologyinthemurineretina.InvOphtVisScie2011,52:3436 2.Bengtson,Aetal;Pharmacokinetics,Tolerability,andPreliminaryEfficacyofPaquinimod(ABR-215757),aNewQuinoline-3-CarboxamideDerivative:studiesinlupus-pronemiceandamulticenter,randomized,double-blind,placebo-controlled,repeat-dose,dose-rangingstudyinpatientswithsystemiclupuserythematosus.ArthritisRheum2012,64:15793.Tati,Retal.ComplementactivationassociatedwithADAMSTS13deficiencyinhumanandmurinethromboticmicroangiopathy.JI2013,191:2184 |
| Storageandstability | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
| Disease | Infectiousdiseases,Nephrology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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