Hycult生物技术/TNF-RI，人，单克隆抗体MR1-2，生物素化/HM2006/50µg
商品编号：
HM2006
品牌：
hycultbiotech
市场价：
¥6960.00
美元价：
4176.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:TNF-RI,Human,mAbMR1-2,biotinylated
Theantibodyreactswiththeextra-cellularpartoftheTNF-RI.Italsoreactswiththesolublereceptor.TNF-RIispresentonmostcelltypesandisconsideredtoplayaprominentroleincellstimulationbyTNF-alpha:InductionofcytotoxicityandotherfunctionsaremediatedlargelyviaTNF-RI.TheantibodycrossreactswithrhesusandcynomolgusnaturalTNF-RI.
Specifications:
| Catalognumber | HM2006 |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 50µg |
| Formulation | 0.5ml(100μg/ml)0.2μmfilteredproteinGpurifiedbiotinylatedantibodysolutioninPBS,containing0.1%bovineserumalbuminand0.02%sodiumazide. |
| Conjugate | Biotin |
| Application | Flowcytometry,Functionalstudies |
| Use | Dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
| Immunogen | ExtracellularpartofTNF-R55 |
| Isotype | MouseIgG1 |
| Species | Human |
| Crossreactivity | Cynomolgusmonkey-Yes,Rhesusmonkey-Yes |
| Alias | Tumornecrosisfactorreceptorsuperfamilymember1A,TumornecrosisfactorreceptortypeI Genename:TNFRSF1A |
| PositiveControl | HumanlymphnodesorPHAactivatedTcells |
| References | 1.Leeuwenberg,JFMetal;SlowreleaseofsolubleTNF-Receptorsbymonocytesinvitro.JImmunol1994,152:4036 2.Leeuwenberg,JFMetal;LipopolysaccharideLPS-mediatedsolubleTNF-ReceptorreleaseandTNF-Receptorexpressionbymonocytes;roleofCD14,LPSbindingproteinandbactericidal/permeABIlity-increasingprotein.JImmnol1994,152:5070 3.Marchetti,Letal;Tumornecrosisfactor(TNF)-mediatedneuroprotectionagainstglutamate-inducedexcitotoxicityisenhancedbyN-methyl-D-aspartatereceptoractivation.EssentialroleofaTNFreceptor2-mediatedphosphatidylinositol3-kinase-dependentNF-kappaBpathway.JBiolChem2004,279:32869 |
| Storageandstability | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
| Disease | Autoimmunity,Gastroenterology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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