Hycult Biotech/RBC，小鼠，单克隆抗体34-3C/HM1120/100µg
商品编号：
HM1120
品牌：
hycultbiotech
市场价：
¥6432.00
美元价：
3859.20
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:RBC,Mouse,mAb34-3C
Themonoclonalantibody34-3Crecognizesanexposedsurfacedeterminantofintactredbloodcells(RBC).Thehigh-affinityanti-RBCmonoclonalantibodyefficientlybindtoFcreceptorsonmacrophagesinducinganemiainvivoduetoarapidFcreceptor(FcyR)-mediatederythrophagocytosisofopsonisedRBCinspleenandlivers.ThecapacityoftheantibodytointeractwithFcyRisresponsIBLeforitshaemolyticactivity.ThemonoclonalantibodyonlyrecognisesantigenicdeterminantsexpressedonMouseRBCandnotonotherspeciesofRBC.
Specifications:
| Catalognumber | HM1120 |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100µg/ml)0.2µmfilteredantibodysolutioninPBS,containing0.1%bovineserum. |
| Application | Flowcytometry,Functionalstudies |
| Use | Forflowcytometrydilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50.Forfunctionalstudies,invitrodilutionshavetobeoptimizedinuser"sexperimentalsetting. |
| Immunogen | RBC |
| Isotype | MouseIgG2a |
| Species | Mouse |
| Crossreactivity | Chicken-No,Human-No,Rabbit-No,Rat-No,Sheep-No |
| PositiveControl | Mouseerythrocytes |
| References | 1.Shibata,Tetal;Monoclonalanti-erythrocyteautoantibodiesderivedfromNZBmicecauseautoimmunehaemolyticanemiabytwodistinctpathogenicmechanisms.Int.Immun.1990,2:1133 2.Fossati-Jimack,Letal;Highpathogenicpotentialoflow-affinityautoantibodiesinexperimentalautoimmunehaemolyticanemia.J.Exp.Med.1990,190:1689 3.Fossati-Jimack,Letal;Selectiveincreaseofautoimmuneepitopeexpressiononagederythrocytesinmice:Implicationsinanti-erythrocyteautoimmuneresponses.J.Autoimmun.2002,18:17 4.AzeredodaSilveira,Setal;ComplementactivationselectivelypotentiatesthepathogenicityoftheIgG2bandIgG3isotypesofahigh-affinityanti-erythrocyteautoantibody.J.Exp.Med.2002,195:665 5.Baudino,Letal;DifferentialcontributionofthreedifferentactivatingIgGFcreceptors(FcyRI,FcyRIIIandFcyRIV)toIgG2a-andIgG2b-inducedautoimmunehaemolyticanemiainmice.J.Immunol.2008,180:1948 |
| StorageandstABIlity | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforatleastoneyear.Theexactexpirydateisindicatedonthelabel. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandfederalrulesintheuseofthisproduct.HycultBiotechisnotresponsibleforanypatentinfringementsthatmightresultfromtheuseorderivationofthisproduct. |
| Disease | Autoimmunity,Infectiousdiseases |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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