Hycult Biotech/EphB1、B2、B3，小鼠，单克隆抗体EfB1-3/HM1113/100µg
商品编号：
HM1113
品牌：
hycultbiotech
市场价：
¥7752.00
美元价：
4651.20
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:EphB1,B2,B3,Mouse,mAbEfB1-3
ThemonoclonalantibodyEfB1-3recognizesthemouseephrinreceptorsEphB1,EphB2andEphB3,118kDa,110kDaand110kDa,respectively.
Erythropoietin-producinghumanhepatocellularcarcinoma(Eph)receptorsandephrinsaremembraneproteins.Theyareclassifiedintotwosubclasses,namelyAandB,accordingtostructuralcharacteristicsandbindingspecificities.Ephreceptorsaretyrosinekinases,whichautophosphorylateuponbindingtotheircognateephrinligands.Ephreceptorsandephrinsarefrequentlyexpressedinreciprocalpatternsthatcorrelatewithcellularboundariesduringembryonicdevelopment.
AuniquefeatureofEph-ephrininteractionsisthattheycanfacilitatebi-directionalcommunicationbetweencells.Ephreceptorsandephrinligandsareinvolvedinvariousanimaldevelopmentprocesses,andimplicatedinsomecancers.Eph-ephrininteractionsmediateavarietyofcontact-dependentphenomenainboththedevelopingandmaturecentralnervoussystem.Theyareinvolvedinneuralcrestcellmigration,hindbrainsegmentation,morphogeneticmomentsduringgastrulation,brainguidanceintheinnerear,retinalganglioncellaxonguidanceandaxonbundlinginthehippocampus.
ThemonoclonalantibodyEfB1-3canalsobeusedtostainculturedspinalcordexplants.
Erythropoietin-producinghumanhepatocellularcarcinoma(Eph)receptorsandephrinsaremembraneproteins.Theyareclassifiedintotwosubclasses,namelyAandB,accordingtostructuralcharacteristicsandbindingspecificities.Ephreceptorsaretyrosinekinases,whichautophosphorylateuponbindingtotheircognateephrinligands.Ephreceptorsandephrinsarefrequentlyexpressedinreciprocalpatternsthatcorrelatewithcellularboundariesduringembryonicdevelopment.
AuniquefeatureofEph-ephrininteractionsisthattheycanfacilitatebi-directionalcommunicationbetweencells.Ephreceptorsandephrinligandsareinvolvedinvariousanimaldevelopmentprocesses,andimplicatedinsomecancers.Eph-ephrininteractionsmediateavarietyofcontact-dependentphenomenainboththedevelopingandmaturecentralnervoussystem.Theyareinvolvedinneuralcrestcellmigration,hindbrainsegmentation,morphogeneticmomentsduringgastrulation,brainguidanceintheinnerear,retinalganglioncellaxonguidanceandaxonbundlinginthehippocampus.
ThemonoclonalantibodyEfB1-3canalsobeusedtostainculturedspinalcordexplants.
Specifications:
| Catalognumber | HM1113 |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100µg/ml)0.2µmfilteredantibodysolutioninPBS,containing0.1%bovineserumalbuminand0.02%sodiumazide. |
| Application | Frozensections,Immunofluorescence,Westernblot |
| Use | ForimmunohistologyandWesternblotting,dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
| Immunogen | RatEphB1-Fc |
| Isotype | MouseIgG1 |
| Species | Mouse |
| Alias | Tyrosine-proteinkinasereceptorEPH-2,HEK6,ELK |
| References | 1.Jevince,Aetal;DistributionofEphBreceptorsandephrin-B1inthedevelopingvertebratespinalcord.JCompNeurol2006,497:734 |
| StorageandstABIlity | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandfederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultfromtheuseorderivationofthisproduct. |
| Disease | Neurologicaldisorders,Tumorimmunology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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