4000-520-616
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当前位置: 首页 > 产品中心 > monoclonal_antibody > Hycult生物技术公司/单核细胞/巨噬细胞,小鼠,单克隆抗体ER-HR3/HM1088/100µg
商品详细Hycult生物技术公司/单核细胞/巨噬细胞,小鼠,单克隆抗体ER-HR3/HM1088/100µg
Hycult生物技术公司/单核细胞/巨噬细胞,小鼠,单克隆抗体ER-HR3/HM1088/100µg
Hycult生物技术公司/单核细胞/巨噬细胞,小鼠,单克隆抗体ER-HR3/HM1088/100µg
商品编号: HM1088
品牌: hycultbiotech
市场价: ¥6432.00
美元价: 3859.20
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Description:Monocytes/Macrophages,Mouse,mAbER-HR3

ThemonoclonalantibodyER-HR3isreactivetothemajorityofmousemonocytesandasubsetofmatureresidentmacrophages,especiallythoselocatedinhemopoieticorgans.WhereasallotherleukocytesareER-HR3negative,upto70%ofcirculatingmonocytesstainpositivewiththismonoclonalantibody.FurThermore,about30%ofbonemarrowcellsexpresstheantigen.OtherER-HR3positivemacrophagescanbefoundinthesplenicredpulp,inthemesentericlymphoidparacortex,interfollicularareasofPeyer"spatchesandbonemarrow.FewER-HR3positivecellsareobservedinthethymiccortexandtheconnectivetissuesofthegastro-intestinaltract,thedermisandtherenalmedulla.EpidermalLangerhanscellsalsoexpresstheantigen.ThemonoclonalantibodyER-HR3canbeusedtoidentifyandlocalizeaverydistinctmaturetissuemacrophagesubpopulationfoundinvariousmouseorgansanditsdistributionpatternisuniquecomparedtothatfromothermacrophage-specificantibodies.TheantibodyisespeciallysuitableforontogenicstudiesbecauseER-HR3positivemacrophagesarecloselyrelatedtohemopoieticislands,especiallyaterythropoieticsites.

Specifications:

CatalognumberHM1088
ProducttypeMonoclonalantibodies
Quantity100µg
Formulation1ml(100µg/ml)0.2µmfilteredantibodysolutioninPBS,containing0.1%bovineserumalbuminand0.02%sodiumazide.
ApplicationFlowcytometry,Frozensections,Paraffinsections
UseForflowcytometryandimmunohistologydilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50.
IsotypeRatIgG2c
SpeciesMouse
References1.deJong,Jetal;Amonoclonalantibody(ER-HR3)againstmurinemacrophages.I.Ontogeny,distributionandenzymehistochemicalcharacterizationofER-HR3-positivecells.CellTissueRes1994,275:5672.deJong,Jetal;Amonoclonalantibody(ER-HR3)againstmurinemacrophages.II.BiochemicalandfunctionalaspectsoftheER-HR3antigen.CellTissueRes1994,275:577
StorageandstABIlityProductshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear.
PrecautionsForresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct.
DiseaseInfectiousdiseases
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。