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Hycult Biotech/Nectin-2, Mouse, mAb 502-57, FITC/HM1052F/100 µg
Hycult Biotech/Nectin-2, Mouse, mAb 502-57, FITC/HM1052F/100 µg
商品编号：
HM1052F
品牌：
hycultbiotech
市场价：
¥11304.00
美元价：
6782.40
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:Nectin-2,Mouse,mAb502-57,FITC
Nectin(originallyisolatedaspoliovirusreceptor-relatedprotein(PRR))isacell-celladhesionmoleculeoftheimmunoglobulinsupergenefamily.NectiniscolocalizedwithafADInatcadherin-basedcell-celladherencejunctionsinvarioustissuesandcelllines.Thenectinfamilyconsistofnectin-1,nectin-2andnectin-3.Nectin-2alsoknownasPRR2orCD112isaplasmamembraneadhesionmoleculelocalizedatadherensjunctionswhichiswidelyexpressedinvariouscelllinesincludingneuronal,endothelial,epithelialandhematopoieticcells.NexttoitsroleinadherensjunctionsitfunctionsasalphaherpusvirusreceptorandactsalsoasintercellularadhesionmoleculeandpseudorABIesvirusreceptor.Disruptionofmousenectin-2leadstoinfertilityofmalemice.Monoclonalantibody502-57hasbeenraisedagainsttheextracellulardomainofmousenectin-2.Theantibodycrossreactswithhumannectin-2.
Specifications:
| Catalognumber | HM1052F |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100μg/ml)0.2μmproteinGpurifiedFITCconjugatedantibodysolutioninPBS,containing1%bovineserumalbuminand0.02%sodiumazide. |
| Conjugate | FITC |
| Application | Frozensections,Immunoassays,Immunofluorescence,Immunoprecipitation,Westernblot |
| ApplicationNotes | F:FixationwithPFAoracetone/methanolisrecommended. IA:HM1052canbeusedasadetectionantibody. W:proteinswereseparatedbySDS-PAGEandelectrophoreticallytransferredontopolyvinylidenefluoridesheets,whichwerethenincubatedwithprimaryantibodies.BindingwasdetectedwithHRP-conjugatedsecondaryantibodiesandWesternblottingdetectionreagents(Ref.3). |
| Use | Dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
| Isotype | RatIgG2a |
| Species | Mouse |
| Crossreactivity | Human-Yes |
| Alias | HerpesvirusentrymediatorB,HerpesvirusentrymediatorB,HveB,MurineherpesvirusentryproteinB,mHveB,Nectincelladhesionmolecule2,Poliovirusreceptorhomolog,Poliovirusreceptor-relatedprotein2,CD112 Genename:Nectin2,Mph,Pvr,Pvrl2,Pvs |
| References | 1.Takahashi,Ketal;Nectin/PRR:Animmunoglobulin-likecelladhesionmoleculerecruitedtocadherin-basedadherensjunctionsthroughinteractionwithafadin,aPDZdomain-containingprotein.JCellBiol1999,145:539 2.Kawabe,Hetal;Pilt,anovelperipheralmembraneproteinattightjunctionsinepithelialcells.JBiolChem2001,276:48350 3.Sugimoto,Metal;Thekeratin-bindingproteinAlbatrossregulatespolarizationofepithelialcells.JCB2008;183:19 |
| Storageandstability | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforatleastoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
| Disease | Infectiousdiseases |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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