Hycult Biotech/JAM-A, Mouse, mAb BV12/HM1050/100 µg
商品编号：
HM1050
品牌：
hycultbiotech
市场价：
¥9288.00
美元价：
5572.80
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:JAM-A,Mouse,mAbBV12
ThemonoclonalantibodyBV12recognizesjunctionaladhesionmolecule-A(JAM-A),alsoknownasJAM-1andthemouseplateletF11-Receptor(F11R),isacelladhesionmolecule(CAM).JAM-Aisamemberoftheimmunoglobulinsuperfamilyfoundonthesurfaceofmouseplateletsandatintercellularjunctionsofendothelialcellsandepithelialcells.JAM-AbelongstogetherwithJAM-B(VE-JAMorJAM-3)andJAM-C(JAM-2)toafamilyofadhesionproteinswithaV-C2immunoglobulindomainorganization.JAMplaysanimportantroleintightjunctionswhereitisinvolvedincell-to-celladhesionthroughhomophilicinteraction.ItcodistributeswithothertightjunctioncomponentsasZO-1,7H6antigen,cingulinandoccludin.InhumanJAM-Aplaysaroleinplateletaggregation,secretion,adhesionandspreADIng.
Specifications:
| Catalognumber | HM1050 |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100µg/ml)0.2µmfilteredantibodysolutioninPBS,containing0.1%bovineserumalbuminand0.02%sodiumazide. |
| Application | Flowcytometry,Immunofluorescence,Immunoprecipitation,Westernblot |
| ApplicationNotes | ThemonoclonalantibodyBV12canbeusedforflowcytometry,Westernblotting,immunoprecipitationandimmunoassays.ThemonoclonalantibodyBV12isalsousefulforimmunofluorescenceonfixedcells. |
| Use | ForflowcytometryandWesternblottingdilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
| Isotype | RatIgG2a |
| Species | Mouse |
| Crossreactivity | Human-No |
| Alias | JAM-1,F11R |
| References | 1.Bazzoni,Getal;InteractionofjunctionaladhesionmoleculewiththetightjunctioncomponentsZO-1,cingulin,andoccludin.JBiolChem2000,275:205202.Martinez-Estrada,Oetal;Oppositeeffectsoftumornecrosisfactorandsolublefibronectinonjunctionaladhesionmolecule-Ainendothelialcells.AmJPhysiolLungCellMolPhysiol2005,288:L1081 |
| StorageandstABIlity | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandfederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultfromtheuseorderivationofthisproduct. |
| Disease | Cardiologyandmetabolism,Tumorimmunology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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