4000-520-616
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当前位置: 首页 > 产品中心 > Tag_antibody > Hycult Biotech/Ficolin-2, Human, mAb GN5, immuno assay antibody/HM2091-IA/0.5 mg
商品详细Hycult Biotech/Ficolin-2, Human, mAb GN5, immuno assay antibody/HM2091-IA/0.5 mg
Hycult Biotech/Ficolin-2, Human, mAb GN5, immuno assay antibody/HM2091-IA/0.5 mg
Hycult Biotech/Ficolin-2, Human, mAb GN5, immuno assay antibody/HM2091-IA/0.5 mg
商品编号: HM2091-IA
品牌: hycultbiotech
市场价: ¥26232.00
美元价: 15739.20
产地: 美国(厂家直采)
公司:
产品分类: 标签抗体
公司分类: Tag_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Description:Ficolin-2,Human,mAbGN5,immunoassayantibody

ThemonoclonalantibodyGN5recognizeshumanFicolin-2,alsoknownasL-ficolin.Ficolinsareafamilyofpatternrecognitionmoleculescontainingbothacollagen-likedomainandafibrinogen-likedomainthatarecapableofactivatingthecomplementsystem,throughassociationwithMASPs,onthesurfaceofmicroorganisms.Inhuman,threeFicolinsareknown:Ficolin-1(M-ficolin),Ficolin-2(L-ficolin),andFicolin-3(H-ficolin).Ficolin-1,ismainlyexpressedbymonocytes,granulocytesandlungcellsandispresentlocallyinareasofinflammation.
Ficolin-2/P35(alsoL-ficolin,ficolinL,EBP-37orhucolin)isproducedprimarilybytheliver.TheassociationbetweenFicolin-2/P35andMASPs/sMAPisCa2+-dependent.MASPsinFicolin-2/P35-MASPcomplexeshaveproteolyticactivitiesforC4,C2andC3.Ficolin-2/P35alsoshowsopsonicactivity.

Specifications:

CatalognumberHM2091-IA
ProducttypeMonoclonalantibodies
Quantity0.5mg
Formulation0.5mgof0.2μmproteinGpurifiedantibodysolutioninPBS(exactconcentrationisindicatedonthelabel).
ApplicationFrozensections,Immunoassays,Immunoprecipitation,Westernblot
ApplicationNotesW:Anon-reducedsampletreatmentandSDS-Pagewasused.Thebandsizeis35kDa.
IHC-F:TissuesectionswerefixedinacetoneandpretreatedwithperoxidaseblockoftheDakokit5min.inthedarkatRTtoquenchendogenousperoxidases.
UseDilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50.
IsotypeMouseIgG1
SpeciesHuman
CrossreactivityRat-Yes
AliasFicolin-2/P35,L-ficolin,ficolinL,EBP-37,hucolin,37kDaelastin-bindingprotein,Collagen/fibrinogendomain-containingprotein2,Ficolin-B,Ficolin-beta
Genename:FCN2,FCNL
References1.Matsushita,Metal;Activationofthelectincomplementpathwaybyficolins.IntImmunopharmacol2001,1:359
2.Matsushita,Metal;ActivationofthelectincomplementpathwaybyH-ficolin(Hakataantigen).JofImmunol2002,168:3502
3.Matsushita,Metal;Theroleofficolinsininnateimmunity.Immunobiol2002,205:490
StorageandstABIlityProductshouldbestoredat4°C.Underrecommendedstorageconditions,productisstableforoneyear.
PrecautionsForresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct.
DiseaseCardiologyandmetabolism,Infectiousdiseases
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。