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Hycult Biotech/Ficolin-2, Human, mAb GN5, immuno assay antibody/HM2091-IA/0.5 mg
Hycult Biotech/Ficolin-2, Human, mAb GN5, immuno assay antibody/HM2091-IA/0.5 mg
商品编号:
HM2091-IA
品牌:
hycultbiotech
市场价:
¥26232.00
美元价:
15739.20
产品分类:
标签抗体
公司分类:
Tag_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description:Ficolin-2,Human,mAbGN5,immunoassayantibody
ThemonoclonalantibodyGN5recognizeshumanFicolin-2,alsoknownasL-ficolin.Ficolinsareafamilyofpatternrecognitionmoleculescontainingbothacollagen-likedomainandafibrinogen-likedomainthatarecapableofactivatingthecomplementsystem,throughassociationwithMASPs,onthesurfaceofmicroorganisms.Inhuman,threeFicolinsareknown:Ficolin-1(M-ficolin),Ficolin-2(L-ficolin),andFicolin-3(H-ficolin).Ficolin-1,ismainlyexpressedbymonocytes,granulocytesandlungcellsandispresentlocallyinareasofinflammation.
Ficolin-2/P35(alsoL-ficolin,ficolinL,EBP-37orhucolin)isproducedprimarilybytheliver.TheassociationbetweenFicolin-2/P35andMASPs/sMAPisCa2+-dependent.MASPsinFicolin-2/P35-MASPcomplexeshaveproteolyticactivitiesforC4,C2andC3.Ficolin-2/P35alsoshowsopsonicactivity.
Ficolin-2/P35(alsoL-ficolin,ficolinL,EBP-37orhucolin)isproducedprimarilybytheliver.TheassociationbetweenFicolin-2/P35andMASPs/sMAPisCa2+-dependent.MASPsinFicolin-2/P35-MASPcomplexeshaveproteolyticactivitiesforC4,C2andC3.Ficolin-2/P35alsoshowsopsonicactivity.
Specifications:
Catalognumber | HM2091-IA |
---|---|
Producttype | Monoclonalantibodies |
Quantity | 0.5mg |
Formulation | 0.5mgof0.2μmproteinGpurifiedantibodysolutioninPBS(exactconcentrationisindicatedonthelabel). |
Application | Frozensections,Immunoassays,Immunoprecipitation,Westernblot |
ApplicationNotes | W:Anon-reducedsampletreatmentandSDS-Pagewasused.Thebandsizeis35kDa. IHC-F:TissuesectionswerefixedinacetoneandpretreatedwithperoxidaseblockoftheDakokit5min.inthedarkatRTtoquenchendogenousperoxidases. |
Use | Dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
Isotype | MouseIgG1 |
Species | Human |
Crossreactivity | Rat-Yes |
Alias | Ficolin-2/P35,L-ficolin,ficolinL,EBP-37,hucolin,37kDaelastin-bindingprotein,Collagen/fibrinogendomain-containingprotein2,Ficolin-B,Ficolin-beta Genename:FCN2,FCNL |
References | 1.Matsushita,Metal;Activationofthelectincomplementpathwaybyficolins.IntImmunopharmacol2001,1:359 2.Matsushita,Metal;ActivationofthelectincomplementpathwaybyH-ficolin(Hakataantigen).JofImmunol2002,168:3502 3.Matsushita,Metal;Theroleofficolinsininnateimmunity.Immunobiol2002,205:490 |
StorageandstABIlity | Productshouldbestoredat4°C.Underrecommendedstorageconditions,productisstableforoneyear. |
Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
Disease | Cardiologyandmetabolism,Infectiousdiseases |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。
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