Hycult Biotech/C3/C3a，人，单克隆抗体474，免疫分析抗体/HM2073-IA/0.5 mg
商品编号：
HM2073-IA
品牌：
hycultbiotech
市场价：
¥20832.00
美元价：
12499.20
产品分类：
标签抗体
公司分类：
Tag_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:C3/C3a,Human,mAb474,immunoassayantibody
Monoclonalantibody474reactswithanepitopeonC3a.TheantibodyreactsbothwithintactC3aswithC3a.Thecomplementsystemisanimportantfactorininnateimmunity.Thethirdcomplementcomponent,C3,iscentraltotheclassical,alternativeandlectinpathwaysofcomplementactivation.ThesynthesisofC3istissue-specificandismodulatedinresponsetoavarietyofstimulatoryagents.AninheriteddeficiencyofC3predisposesthepersontofrequentassaultsofbacterialinfections.ProteolysisbycertainenzymesresultsinthecleavageofC3intoC3aandC3b.C3aisamediatoroflocalinflammatoryprocesses.C3adoesinducesmoothmusclecontraction,increasesvascularpermeABIlity,andcauseshistaminereleasefrommastcellsandbasophilicleukocytes
Specifications:
| Catalognumber | HM2073-IA |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 0.5mg |
| Formulation | 0.5mgof0.2μmfilteredproteinGpurifiedantibodysolutioninPBSwithaconcentrationofatleast0.5mg/ml(exactconcentrationisindicatedonthelabel). |
| Application | Immunoassays,Westernblot |
| ApplicationNotes | W:diabeticserumproteinswereseparatedonPAGE-gelandtransferredtonitrocellulose |
| Use | Dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
| Immunogen | C3a |
| Isotype | MouseIgG1 |
| Species | Human |
| Alias | Complementcomponent3 |
| PositiveControl | Humanserum |
| NegativeControl | C3-deficientserum |
| References | 1.Hartmann,Hetal;RapidquantificationofC3aandC5ausingacombinationofchromatographicandimmunoassayprocedures.JImmunolMethods1993,166:35 2.Stöve,Setal;Re-evaluationofthestorageconditionsforbloodsampleswhichareusedfordeterminationofcomplementactivation.JImmunolMethods1995,182:1 3.Li,Retal.Localized-statisticalquantificationofhumanserumproteomeassociatedwithtype2diabetes.Plosone2008,3:e3224 4.Shi,Letal.DiscoveryandidentificationofpotentialbioMarkersofpediatricacutelymphoblasticleukemia.Proteomescience2009,7:7 |
| Storageandstability | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
| Disease | Infectiousdiseases,Nephrology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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