 
								Hycult Biotech/TNF-RI,人,单克隆抗体MR1-2,功能研究抗体,低内毒素/HM2005-FS/0.5 mg
								
										商品编号:
										HM2005-FS
									
									
										品牌:
										hycultbiotech
									
									
								
										市场价:
										¥26232.00
									
									
										美元价:
										15739.20
									
								
										产品分类:
										标签抗体
									
									
										公司分类:
										Tag_antibody
									
								
										联系Q Q:
										3392242852
									
									
										电话号码:
										4000-520-616
									
								
										电子邮箱:
										info@ebiomall.com
									
									商品介绍
						Description:TNF-RI,Human,mAbMR1-2,functionalstudyantibody,lowendotoxin
TheantibodyMR1-2reactswiththeextra-cellularpartoftheTNF-RI.Italsoreactswiththesolublereceptor.TNF-RIispresentonmostcelltypesandisconsideredtoplayaprominentroleincellstimulationbyTNF-alpha:InductionofcytotoxicityandotherfunctionsaremediatedlargelyviaTNF-RI.TheantibodycrossreactswithrhesusandcynomolgusnaturalTNF-RI.
Specifications:
| Catalognumber | HM2005-FS | 
|---|---|
| Producttype | Monoclonalantibodies | 
| Quantity | 0.5mg | 
| Formulation | 0.5mg(100μg/ml)0.2μmfilteredproteinGpurifiedantibodysolutioninPBSwithaconcentrationofatleast0.5mg/ml(exactconcentrationisindicatedonthelabel).Theendotoxinconcentrationis<24EU/mg,determinedwithHIT302LALAssay. | 
| Application | Flowcytometry,Functionalstudies | 
| Use | Dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. | 
| Immunogen | ExtracellularpartofTNF-R55 | 
| Isotype | MouseIgG1 | 
| Species | Human | 
| Crossreactivity | Cynomolgusmonkey-Yes,Rhesusmonkey-Yes | 
| Alias | Tumornecrosisfactorreceptorsuperfamilymember1A,TumornecrosisfactorreceptortypeI Genename:TNFRSF1A | 
| PositiveControl | HumanlymphnodesorPHAactivatedTcells | 
| References | 1.Leeuwenberg,JFMetal;SlowreleaseofsolubleTNF-Receptorsbymonocytesinvitro.JImmunol1994,152:4036 2.Leeuwenberg,JFMetal;LipopolysaccharideLPS-mediatedsolubleTNF-ReceptorreleaseandTNF-Receptorexpressionbymonocytes;roleofCD14,LPSbindingproteinandbactericidal/permeABIlity-increasingprotein.JImmnol1994,152:5070 3.Marchetti,Letal;Tumornecrosisfactor(TNF)-mediatedneuroprotectionagainstglutamate-inducedexcitotoxicityisenhancedbyN-methyl-D-aspartatereceptoractivation.EssentialroleofaTNFreceptor2-mediatedphosphatidylinositol3-kinase-dependentNF-kappaBpathway.JBiolChem2004,279:32869 | 
| Storageandstability | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. | 
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HbtisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. | 
| Disease | Autoimmunity,Gastroenterology | 
品牌介绍
						荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。
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