Hycult Biotech/TNF-RI,人,单克隆抗体MR1-2,功能研究抗体,低内毒素/HM2005-FS/0.5 mg
商品编号:
HM2005-FS
品牌:
hycultbiotech
市场价:
¥26232.00
美元价:
15739.20
产品分类:
标签抗体
公司分类:
Tag_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description:TNF-RI,Human,mAbMR1-2,functionalstudyantibody,lowendotoxin
TheantibodyMR1-2reactswiththeextra-cellularpartoftheTNF-RI.Italsoreactswiththesolublereceptor.TNF-RIispresentonmostcelltypesandisconsideredtoplayaprominentroleincellstimulationbyTNF-alpha:InductionofcytotoxicityandotherfunctionsaremediatedlargelyviaTNF-RI.TheantibodycrossreactswithrhesusandcynomolgusnaturalTNF-RI.
Specifications:
Catalognumber | HM2005-FS |
---|---|
Producttype | Monoclonalantibodies |
Quantity | 0.5mg |
Formulation | 0.5mg(100μg/ml)0.2μmfilteredproteinGpurifiedantibodysolutioninPBSwithaconcentrationofatleast0.5mg/ml(exactconcentrationisindicatedonthelabel).Theendotoxinconcentrationis<24EU/mg,determinedwithHIT302LALAssay. |
Application | Flowcytometry,Functionalstudies |
Use | Dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
Immunogen | ExtracellularpartofTNF-R55 |
Isotype | MouseIgG1 |
Species | Human |
Crossreactivity | Cynomolgusmonkey-Yes,Rhesusmonkey-Yes |
Alias | Tumornecrosisfactorreceptorsuperfamilymember1A,TumornecrosisfactorreceptortypeI Genename:TNFRSF1A |
PositiveControl | HumanlymphnodesorPHAactivatedTcells |
References | 1.Leeuwenberg,JFMetal;SlowreleaseofsolubleTNF-Receptorsbymonocytesinvitro.JImmunol1994,152:4036 2.Leeuwenberg,JFMetal;LipopolysaccharideLPS-mediatedsolubleTNF-ReceptorreleaseandTNF-Receptorexpressionbymonocytes;roleofCD14,LPSbindingproteinandbactericidal/permeABIlity-increasingprotein.JImmnol1994,152:5070 3.Marchetti,Letal;Tumornecrosisfactor(TNF)-mediatedneuroprotectionagainstglutamate-inducedexcitotoxicityisenhancedbyN-methyl-D-aspartatereceptoractivation.EssentialroleofaTNFreceptor2-mediatedphosphatidylinositol3-kinase-dependentNF-kappaBpathway.JBiolChem2004,279:32869 |
Storageandstability | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HbtisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
Disease | Autoimmunity,Gastroenterology |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。
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