4000-520-616
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当前位置: 首页 > 产品中心 > Tag_antibody > Hycult Biotech/TNF-RI,人,单克隆抗体MR1-2,功能研究抗体,低内毒素/HM2005-FS/0.5 mg
商品详细Hycult Biotech/TNF-RI,人,单克隆抗体MR1-2,功能研究抗体,低内毒素/HM2005-FS/0.5 mg
Hycult Biotech/TNF-RI,人,单克隆抗体MR1-2,功能研究抗体,低内毒素/HM2005-FS/0.5 mg
Hycult Biotech/TNF-RI,人,单克隆抗体MR1-2,功能研究抗体,低内毒素/HM2005-FS/0.5 mg
商品编号: HM2005-FS
品牌: hycultbiotech
市场价: ¥26232.00
美元价: 15739.20
产地: 美国(厂家直采)
公司:
产品分类: 标签抗体
公司分类: Tag_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Description:TNF-RI,Human,mAbMR1-2,functionalstudyantibody,lowendotoxin

TheantibodyMR1-2reactswiththeextra-cellularpartoftheTNF-RI.Italsoreactswiththesolublereceptor.TNF-RIispresentonmostcelltypesandisconsideredtoplayaprominentroleincellstimulationbyTNF-alpha:InductionofcytotoxicityandotherfunctionsaremediatedlargelyviaTNF-RI.TheantibodycrossreactswithrhesusandcynomolgusnaturalTNF-RI.

Specifications:

CatalognumberHM2005-FS
ProducttypeMonoclonalantibodies
Quantity0.5mg
Formulation0.5mg(100μg/ml)0.2μmfilteredproteinGpurifiedantibodysolutioninPBSwithaconcentrationofatleast0.5mg/ml(exactconcentrationisindicatedonthelabel).Theendotoxinconcentrationis<24EU/mg,determinedwithHIT302LALAssay.
ApplicationFlowcytometry,Functionalstudies
UseDilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50.
ImmunogenExtracellularpartofTNF-R55
IsotypeMouseIgG1
SpeciesHuman
CrossreactivityCynomolgusmonkey-Yes,Rhesusmonkey-Yes
AliasTumornecrosisfactorreceptorsuperfamilymember1A,TumornecrosisfactorreceptortypeI
Genename:TNFRSF1A
PositiveControlHumanlymphnodesorPHAactivatedTcells
References1.Leeuwenberg,JFMetal;SlowreleaseofsolubleTNF-Receptorsbymonocytesinvitro.JImmunol1994,152:4036
2.Leeuwenberg,JFMetal;LipopolysaccharideLPS-mediatedsolubleTNF-ReceptorreleaseandTNF-Receptorexpressionbymonocytes;roleofCD14,LPSbindingproteinandbactericidal/permeABIlity-increasingprotein.JImmnol1994,152:5070
3.Marchetti,Letal;Tumornecrosisfactor(TNF)-mediatedneuroprotectionagainstglutamate-inducedexcitotoxicityisenhancedbyN-methyl-D-aspartatereceptoractivation.EssentialroleofaTNFreceptor2-mediatedphosphatidylinositol3-kinase-dependentNF-kappaBpathway.JBiolChem2004,279:32869
StorageandstabilityProductshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear.
PrecautionsForresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HbtisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct.
DiseaseAutoimmunity,Gastroenterology
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。