Hycult Biotech/CD14,小鼠,单克隆抗体Sa14-2,功能研究抗体,低内毒素/HM1060-FS/0.5 mg
商品编号:
HM1060-FS
品牌:
hycultbiotech
市场价:
¥23664.00
美元价:
14198.40
产品分类:
标签抗体
公司分类:
Tag_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Description:CD14,Mouse,mAbSa14-2,functionalstudyantibody,lowendotoxin
ThemonoclonalantibodySa14-2reactswiththemousemonocyteMarkerCD14,a53kDaglycoprotein.CD14isaglycophosphatidylinositol-linkedprotein,whichispartoftheLPSreceptorcomplex.CD14bindslipopolysaccharide(LPS)andassuch,actsasapatternrecognitionreceptor(PRR).CD14hasalsobeensuggestedtomediatephagocytosisofbacteriaanapoptoticcells.CD14isinvolvedintheendotoxinmediatedreleaseofTumorNecrosisFactor-alphabymonocyticcells.CD14ispresentonmostmonocyticandmacrophagelikecelltypes:monocytes,macrophages,Kupffercells,pleuralphagocyticcellsanddendriticreticularcells.CD14ispresentinlowdensityonasubpopulationofgranulocytesandactivatedortransformedB-cells.
Specifications:
Catalognumber | HM1060-FS |
---|---|
Producttype | Monoclonalantibodies |
Quantity | 0.5mg |
Formulation | 0.5mg(100 µg/ml)0.2µmfilteredantibodysolutioninPBS(exactconcentrationisindicatedonthelabel) |
Application | Flowcytometry,Functionalstudies,Immunofluorescence,Immunoprecipitation,Westernblot |
Use | ForflowcytometryandWesternblottingdilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
Immunogen | CD14transfectant |
Isotype | RatIgG2a |
Species | Mouse |
Alias | MonocytedifferentiationantigenCD14 |
PositiveControl | RAW-cells |
References | Hajishengallis,Getal;Porphyromonasgingivalisfimbriaeproactivelymodulatebeta2integrinadhesiveactivityandpromotebindingtoandinternalizationbymacrophages.InfectImmun2006,74:5658 |
StorageandstABIlity | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandfederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultfromtheuseorderivationofthisproduct. |
Disease | Infectiousdiseases |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。
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