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商品详细Hycult Biotech/sCD59, Human, ELISA kit | Hycult Biotech/HK374-01
Hycult Biotech/sCD59, Human, ELISA kit  | Hycult Biotech/HK374-01
Hycult Biotech/sCD59, Human, ELISA kit | Hycult Biotech/HK374-01
商品编号: HK374-01
品牌: hycultbiotech
市场价: ¥12660.00
美元价: 7596.00
产地: 美国(厂家直采)
公司:
产品分类: 夹心法ELISA
公司分类: Sandwich_method_ELISA
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. Complement activation ultimately leads to formation of the cytotoxic, poreforming membrane attack complex (MAC), the main effector of complement-mediated tissue damage. Insertion of the MAC into cell membranes induces the release of cytokines and growth factors that promote inflammation, thrombosis, and cell proliferation. CD59 is a complement regulatory protein ubiquitously expressed on mammalian cell surfaces and it specifically inhibits MAC formation and thereby protects “self” cells from complement-mediated damage. The protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in the CD59 gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. CD59 was demonstrated to be present in plasma/serum of healthy individuals in levels ranging from 22 to 119 ng/ml.
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登,从1994开始制造检测抗体和蛋白质,主要侧重与病理学诊断有关的全套产品研发,既有纯化的重组蛋白和多肽,也有单抗和多抗,是世界一流的先天免疫领域的研究试剂制造商。