Hycult Biotech/IFN-gamma, Mouse, mAb F1/HM1003-01/100 µg
商品编号：
HM1003-01
品牌：
hycultbiotech
市场价：
¥6432.00
美元价：
3859.20
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:IFN-gamma,Mouse,mAbF1
MonoclonalantibodyF1bindsbothnaturalandrecombinantmousegammaInterferon.Itsbindingactivityhasbeendemonstratedinvitroandinvivo.F1antibodieshavebeendemonstratedtobeabletoinhibitinflammatoryresponsestobacteriallipopolysaccharides.TheseantibodieswerefurThermoreshowntoinhibitShwartzmanreactionsandtoprotectNZBmiceagainstspontaneousdevelopmentofautoimmunedisease.Theneutralizingactivityoftheantibodyhasbeendemonstratedasbeingpoorinanti-viralassays.Ifaneutralizingantibodyisspecificallydesired,werecommendtheuseofanotherantibodyavailablefromHycultBiotech,namelyF3(prod.codeHM1005)whichrecognizesadifferentepitopeonthemurinegammaInterferonmoleculeandincontrasttoF1,exhibitsstrongneutralizingactivity.Theantibodydoesnotreactwithratorhumangammainterferon
Specifications:
| Catalognumber | HM1003-01 |
|---|---|
| Producttype | Monoclonalantibodies |
| Quantity | 100µg |
| Formulation | 1ml(100 µg/ml)0.2 µmfilteredantibodysolutioninPBS,containing0.1%bovineserumalbuminand0.02%sodiumazide. |
| Application | Functionalstudies,Immunoassays,Immunoprecipitation |
| Use | TheantibodycanbeusedforthepurificationorimmunochemicalinvestigationofmousegammaInterferonandstructuralstudies.Furthermoretheantibodyisusefulforimmunoprecipitationandasatracerantibodyinimmunoassayprocedures. |
| Isotype | RatIgG2a |
| Species | Mouse |
| References | 1.Armstrong,JAetal;Semi-micro,dye-bindingassayforrabbitinterferon.JApplMicrobiol1971,21:723 2.vanTiel,FHetal;DetectionofSemlikiForestvirusincellculturebyuseofanenzymeimmunoassaywithperoxidase-labeledmonoclonalantibodiesspecificforglycoproteinsE1andE2.JClinMicrobiol1984,20:387 3.Dijkmans,Retal;HeterogeneityofChinesehamsterovarycell-producedrecombinantmurineinterferon-gamma.JBiolChem1987,262:2528 4.Heremans,Hetal;Regulationbyinterferonsofthelocalinflammatoryresponsetobacteriallipopolysaccharide.JImmunol1987,138:4175 5.Billiau,Aetal;anti-interferon-gammaantibodyprotectsmiceagainstthegeneralizedShwartzmanreaction.EurJImmunol1987,17:1851 6.Jacob,COetal;invivotreatmentof(NZBXNZW)F1lupus-likenephritiswithmonoclonalantibodytogammainterferon.JExpMed1987,166:798 |
| StorageandstABIlity | Lyophilizedproductshouldbestoredat4 °C.Storestocksolutioninaliquotsat-20 °C.Repeatedfreezeandthawcycleswillcauselossofactivity.Underrecommendedstorageconditions,productisstableforoneyear. |
| Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
| Disease | Autoimmunity,Infectiousdiseases |
品牌介绍
荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。
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